...
Analytical software technical information
The B4C System analytical software produces information output such as estimated P2/P1 ratio variation over time, surrogate ICP waveform signal over time, pulse morphology as average per minute with estimated parameters of P2/P1 ratio, number of useful pulses, heart rate (bpm), and normalized time to peak.
Calculations are done via processing algorithms that receive raw data from the B4C System sensor and generates a processed PDF report with the surrogate ICP waveform and estimtated estimated associated waveform parameters. The automated analysis, done for each minute at a time, includes all steps briefly described below which were developed based on established principles and methods described in literature, to isolate the desired ICP waveform signal for consistent processing:
...
Invasive ICP’s percussion wave (A1) timing (T1) is almost the corresponding ABP’s waveform first peak
Invasive ICP’s notch (A3) timing (T3) is closely related to ABP’s dicrotic notch
Invasive ICP’s tidal wave (A2) timing (T2) is estimated to be midway between ABP’s T3 and T1
Based on this observation an algorithm was developed that estimates P1 and P2 amplitudes for the invasive ICP waveform, as well as the BcSs-PICNI-2000 (B4C Sensor) waveforms, based on the concurrent ABP pulse’s T1 and T2 normalized timings (Figure 07). This allowed for indirect (surrogate) P1 and P2 estimation when they are not visually identifiable in the invasive ICP.
...